5-METHYL-7-PHENYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLAMINE
5-Methyl-7-phenyl-[1,2,4]triazolo[1,5-a]-pyrimidin-2-ylamine
CAS: 72966-19-9
Molecular Formula: C12H11N5
5-METHYL-7-PHENYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLAMINE - Names and Identifiers
5-METHYL-7-PHENYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLAMINE - Physico-chemical Properties
| Molecular Formula | C12H11N5 |
| Molar Mass | 225.25 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD03856667 |
5-METHYL-7-PHENYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLAMINE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
5-METHYL-7-PHENYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YLAMINE - Introduction
5-Methyl-7-phenyl-[1,2,4]triazolo[1,5-a]-pyrimidin-2-ylamine is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Molecular formula: C14H12N6
-Molecular weight: 264.28g/mol
-Appearance: White solid
-Melting point: 175-178°C
-Solubility: Soluble in common organic solvents, such as chloroform, methanol and dichloromethane.
Use:
5-Methyl-7-phenyl-[1,2,4]triazolo[1,5-a]-pyrimidin-2-ylamine is commonly used in research and development in the field of medicinal chemistry. It can be used as a starting material in organic synthesis for the synthesis of other biologically active compounds, for example as a precursor for anticancer drugs or antimicrobial drugs.
Preparation Method:
5-Methyl-7-phenyl-[1,2,4]triazolo[1,5-a]-pyrimidin-2-ylamine can be prepared in many ways, one of which is as follows:
1. 4-bromobenzoyl isocyanate methyl ester was prepared by the reaction of 4-bromobenzoic acid and methyl isocyanate.
2.4-bromobenzoyl isocyanate methyl ester reacts with aminopyrimidine to generate 4-bromobenzoyl aminopyrimidine.
3. 4-Bromobenzoylaminopyrimidine is reacted with sodium azide to prepare 5-methyl lexicon.
4.5-Methyl ^-^ is reacted with N-phenylcycloalkylamine to produce the final target compound.
Safety Information:
There is relatively little information on the toxicity and hazards of 5-Methyl-7-phenyl-[1,2,4]triazolo[1,5-a]-pyrimidin-2-ylamine. However, the following safety precautions should be taken when using or handling the compound:
-Need to operate in a well-ventilated place to avoid inhaling its vapor or dust.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Use personal protective equipment, such as lab gloves and eye protection.
-Follow relevant chemical handling and storage specifications.
Nature:
-Molecular formula: C14H12N6
-Molecular weight: 264.28g/mol
-Appearance: White solid
-Melting point: 175-178°C
-Solubility: Soluble in common organic solvents, such as chloroform, methanol and dichloromethane.
Use:
5-Methyl-7-phenyl-[1,2,4]triazolo[1,5-a]-pyrimidin-2-ylamine is commonly used in research and development in the field of medicinal chemistry. It can be used as a starting material in organic synthesis for the synthesis of other biologically active compounds, for example as a precursor for anticancer drugs or antimicrobial drugs.
Preparation Method:
5-Methyl-7-phenyl-[1,2,4]triazolo[1,5-a]-pyrimidin-2-ylamine can be prepared in many ways, one of which is as follows:
1. 4-bromobenzoyl isocyanate methyl ester was prepared by the reaction of 4-bromobenzoic acid and methyl isocyanate.
2.4-bromobenzoyl isocyanate methyl ester reacts with aminopyrimidine to generate 4-bromobenzoyl aminopyrimidine.
3. 4-Bromobenzoylaminopyrimidine is reacted with sodium azide to prepare 5-methyl lexicon.
4.5-Methyl ^-^ is reacted with N-phenylcycloalkylamine to produce the final target compound.
Safety Information:
There is relatively little information on the toxicity and hazards of 5-Methyl-7-phenyl-[1,2,4]triazolo[1,5-a]-pyrimidin-2-ylamine. However, the following safety precautions should be taken when using or handling the compound:
-Need to operate in a well-ventilated place to avoid inhaling its vapor or dust.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Use personal protective equipment, such as lab gloves and eye protection.
-Follow relevant chemical handling and storage specifications.
Last Update：2024-04-09 21:54:55
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